Bilateral paravertebral block for improved recovery after open heart surgery

Explore if paravertebral nerve blocks (a proven pain control method) done before open cardiac surgery, works well for improving patients quality of recovery and satisfaction.

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About the study

Principal investigator

Dr. Terry Sun

Cardiac Anesthesiologist

Area(s) of medical focus

Heart

Surgical

Condition(s)

Coronary artery disease

Heart valve disorders

Nerve conditions

Period of enrollment

2023-10-09 - 2026-10-09

Participating sites

St. Paul's Hospital

Purpose of trial

The purpose of this study is to see if a nerve block called paravertebral block, done before the surgery, works well for improving pain control and overall satisfaction after heart surgery. 

As a background, paravertebral blocks are widely used in anesthesia for pain control after thoracic and breast surgery. This block has been safely used in patients undergoing heart surgery and found to be anecdotally useful. We want to formally test if this nerve block compared to no nerve block can help patients to recover after cardiac surgery. 

Pain after cardiac surgery can be severe in the first 2 days. Classically we use opioids/narcotics to treat pain but it can be associated with nausea, vomiting, delirium, sedation and constipation. Nerve blocks have the potential to provide better pain relief with improved side effect profile. 

Patients will be randomized to get the paravertebral block or a sham block, where we inject salt water into their back muscle. It is a randomized and blinded controlled trial. 

Eligibility

  • Age 19 years or older 
  • Scheduled for open heart surgery 
  • English-speaking 
  • Pass a cognitive screening test

Contact information

Additional Information

Study Phase

Phase 4/ Post Market