Castleman Disease Registry & Biobank

To collect blood samples from participants with Castleman's Disease and ship these samples to the Castleman Disease Collaborative Network for research purposes.

Illustration of a researcher looking through a microscope

About the study

Principal investigator

Dr. Heather Leitch

MD, PhD, FRCPC, Clinical Professor, Department of Medicine, UBC, Director, Hematology/Oncology Research, St. Paul’s Hospital, Hematologist, St. Paul’s Hospital

Area(s) of medical focus

Allergy & Immune System

Condition(s)

Autoimmune diseases

Period of enrollment

2024-03-24 - 2029-12-31

Participating sites

St. Paul's Hospital

Purpose of trial

The Castleman Disease Collaborative Network is creating a biobank called Castlebank for the purpose of supporting researchers to study the cause of Castleman disease and to develop treatments. The biobank collects blood and other samples.

Our site at St. Paul's Hospital will only participate in the biobank (Castlebank) portion of this study. Our site will collect one blood sample from the participant and ship the sample to the CDCN research site.

The purpose of the CDCN study is to aid researchers in understanding the causes of Castleman disease and to develop treatments based on their findings. Specifically, the goal of the biobank portion of the study is to generate a biobank to support current and future research studies aimed at uncovering the genetic, cellular, biochemical and molecular abnormalities that drive CD pathogenesis.

Eligibility

Inclusion Criteria: 

  • Participants who are diagnosed with Castleman disease by a physician would be able to participate in the study
  • Only participants 19 years or older will be eligible for the study

Exclusion Criteria:

  • All individuals whose medical or psychological conditions (such as a mental handicap) would, in the opinion of the Principal Investigator, compromise the subject’s safety or successful participation in the study
  • All individuals who do not speak English and for which a translator is not available

Contact information

Co-Investigators

Dr. Lynda Foltz, Dr. Khaled Ramadan